Call for Papers

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The rapid evolution of intelligent communication networks that interacts with natural biological systems increasingly depends on the seamless exchange of information across molecular, biological, and electromagnetic domains, spanning multiple spatial, temporal, and functional scales, from nanoscale biochemical interactions to large-scale networked infrastructures. These multi-scale molecular and biological communication systems are expected to play a critical role in shaping future network architectures, as they provide the fundamental mechanisms that enable information flow between the physical, biological, and cyber domains. Such systems will become an essential part of future intelligent networks, supporting transformative applications in precision medicine, environmental monitoring, human-machine symbiosis, bio-cyber-physical systems, and the next-generation Internet of Things.

At the molecular and biological scales, information transmission relies on physical, chemical, and biological mechanisms that operate in complex and dynamic environments, such as within living tissues or cellular networks. At larger scales, electromagnetic communication technologies provide high-speed, high-capacity connectivity between biological entities, sensors, and cyber-physical infrastructures. Bridging these domains requires new theoretical foundations, multi-scale architectures, and intelligent algorithms that ensure reliable, secure, and energy-efficient communication across vastly different scales and modalities.

This Special Issue aims to foster cross-disciplinary research that integrates insights from communication engineering, bioengineering, computer science and engineering, materials science, and related fields to address the foundational, algorithmic, architectural, and experimental challenges of multi-scale molecular and biological communications. We particularly encourage contributions that link nanoscale biological mechanisms with large-scale intelligent network infrastructures, advancing both fundamental understanding and practical technologies for future bio-cyber communication systems. Topics of interest include, but are not limited to:

• Multi-scale architectures integrating molecular, biological, and electromagnetic communication domains
• Cross-domain communication interfaces, including molecular-THz, molecular–RF, biological–optical, and other hybrid modalities
• Molecular and biological communication mechanisms, modeling, and information-theoretical analysis across scales
• Multi-scale channel modeling and signal processing for heterogeneous nano-to-macro networks
• AI/machine learning-enabled algorithms, including federated learning, digital twins, and generative models, for multi-scale system optimization
• Experimental platforms and testbeds demonstrating molecular, biological, and cross-scale communication concepts
• Security, privacy, and trust frameworks for multi-domain and bio-cyber communication systems
• Energy-efficient modulation, coding, and synchronization schemes for multi-scale networks
• Protocols, standards, and interoperability frameworks bridging molecular, biological, and macro communication layers
• Interdisciplinary applications in medicine, robotics, environmental sensing, agriculture, and human–machine interfaces

Submission Guidelines

Prospective authors should submit their manuscripts following the IEEE TMBMC guidelines. Authors should submit a manuscript through Manuscript Central.

Important Dates

Manuscript Submission Deadline: 1 April 2026
First Notification: 1 June 2026
Acceptance Notification: 31 August 2026
Final Manuscript Due: 15 September 26
Publication Date: December 2026

Guest Editors

Yu Huang (Lead Guest Editor)
Guangzhou University, China

Yuankun Tang
Northwest Normal University, China

Changmin Lee
Newratek Inc., South Korea

Kun Yang
University of Essex, UK

Goo Jun
University of Texas Health Science Center Houston, USA